Transferrin-Binding Protein B of Neisseria meningitidis: Sequence-Based Identification of the Transferrin-Binding Site Confirmed by Site-Directed Mutagenesis

A sequence-based prediction method was employed to identify three ligand-binding domains in transferrin-binding protein B (TbpB) of Neisseria meningitidis strain B16B6. Site-directed mutagenesis of residues located in these domains has led to the identification of two domains, amino acids 53 to 57 a...

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Detalhes bibliográficos
Main Authors: Renauld-Mongénie, Geneviève, Lins, Laurence, Krell, Tino, Laffly, Laure, Mignon, Michèle, Dupuy, Monique, Delrue, Rose-May, Guinet-Morlot, Françoise, Brasseur, Robert, Lissolo, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Molecular Biology of Pathogens
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC321495/
https://ncbi.nlm.nih.gov/pubmed/14729713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.3.850-857.2004
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