Breast Milk-Transforming Growth Factor-β(2) Specifically Attenuates IL-1β-Induced Inflammatory Responses in the Immature Human Intestine via an SMAD6- and ERK-Dependent Mechanism

BACKGROUND: Breast milk is known to protect the infant against infectious and immuno-inflammatory diseases, but the mechanisms of this protection are poorly understood. Objectives: We hypothesized that transforming growth factor-β(2) (TGF-β(2)), an immunoregulatory cytokine abundant in breast milk,...

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Hlavní autoři: Rautava, Samuli, Nanthakumar, N. Nanda, Dubert-Ferrandon, Alix, Lu, Lei, Rautava, Jaana, Walker, W. Allan
Médium: Artigo
Jazyk:Inglês
Vydáno: S. Karger AG 2011
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Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214931/
https://ncbi.nlm.nih.gov/pubmed/20881435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000314109
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