Biological functions of p53 isoforms through evolution: lessons from animal and cellular models

The TP53 tumour-suppressor gene is expressed as several protein isoforms generated by different mechanisms, including use of alternative promoters, splicing sites and translational initiation sites, that are conserved through evolution and within the TP53 homologues, TP63 and TP73. Although first de...

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Detalhes bibliográficos
Main Authors: Marcel, V, Dichtel-Danjoy, M-L, Sagne, C, Hafsi, H, Ma, D, Ortiz-Cuaran, S, Olivier, M, Hall, J, Mollereau, B, Hainaut, P, Bourdon, J-C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214904/
https://ncbi.nlm.nih.gov/pubmed/21941372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.120
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