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Replicative Aging Induces Endothelial to Mesenchymal Transition in Human Aortic Endothelial Cells: Potential Role of Inflammation

Thickening of the intimal layer of arteries characterized by expression of smooth muscle α-actin (SMαA), collagen deposition, and inflammation is an important pathophysiological change with aging assumed to be mediated by smooth muscle cells migrating from the medial layer. We tested the novel hypot...

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Detalhes bibliográficos
Main Authors: Fleenor, Bradley S., Marshall, Kurt D., Rippe, Catarina, Seals, Douglas R.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214888/
https://ncbi.nlm.nih.gov/pubmed/21985896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000329681
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