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Are Aβ and Its Derivatives Causative Agents or Innocent Bystanders in AD?

Alzheimer's disease (AD) is characterized by neurodegeneration in neocortical regions of the brain. Currently, Aβ-based theories, including amyloid depositions and soluble Aβ, form the basis of most therapeutic approaches to AD. It remains unclear, however, whether Aβ and its derivatives are th...

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Detalhes bibliográficos
Autor principal: Robakis, Nikolaos K.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214827/
https://ncbi.nlm.nih.gov/pubmed/20160455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000266476
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