Llwytho...

Nickel-catalyzed Asymmetric α-Arylation and Heteroarylation of Ketones with Chloroarenes: Effect of Halide on Selectivity, Oxidation State and Room Temperature Reactions

We report the α-arylation of ketone enolates with a range of aryl chlorides with enantioselectivities from 90% to 99% catalyzed by the combination of Ni(COD)(2) and (R)-BINAP, and the coupling of ketone enolates with a range of heteroaryl chlorides with enantioselectivities up to 99% catalyzed by Ni...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ge, Shaozhong, Hartwig, John F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214653/
https://ncbi.nlm.nih.gov/pubmed/21916501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2082087
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