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RNase MRP Cleaves the CLB2 mRNA To Promote Cell Cycle Progression: Novel Method of mRNA Degradation

RNase mitochondrial RNA processing (RNase MRP) mutants have been shown to have an exit-from-mitosis defect that is caused by an increase in CLB2 mRNA levels, leading to increased Clb2p (B-cyclin) levels and a resulting late anaphase delay. Here we describe the molecular defect behind this delay. CLB...

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Detalles Bibliográficos
Main Authors: Gill, Tina, Cai, Ti, Aulds, Jason, Wierzbicki, Sara, Schmitt, Mark E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC321458/
https://ncbi.nlm.nih.gov/pubmed/14729943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.3.945-953.2004
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