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RanBP2/Nup358 Provides a Major Binding Site for NXF1-p15 Dimers at the Nuclear Pore Complex and Functions in Nuclear mRNA Export

Metazoan NXF1-p15 heterodimers promote the nuclear export of bulk mRNA across nuclear pore complexes (NPCs). In vitro, NXF1-p15 forms a stable complex with the nucleoporin RanBP2/Nup358, a component of the cytoplasmic filaments of the NPC, suggesting a role for this nucleoporin in mRNA export. We sh...

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Udgivet i:Mol Cell Biol
Principais autores: Forler, Daniel, Rabut, Gwénaël, Ciccarelli, Francesca D., Herold, Andrea, Köcher, Thomas, Niggeweg, Ricarda, Bork, Peer, Ellenberg, Jan, Izaurralde, Elisa
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2004
Fag:
Nucleocytoplasmic Communication
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321439/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14729961/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.3.1155-1167.2004
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