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Ginsenoside-Rg1 mediates a hypoxia-independent upregulation of hypoxia-inducible factor-1α to promote angiogenesis

Hypoxia-inducible factor (HIF-1) is the key transcription regulator for multiple angiogenic factors and is an appealing target. Ginsenoside-Rg1, a nontoxic saponin isolated from the rhizome of Panax ginseng, exhibits potent proangiogenic activity and has the potential to be developed as a new angiot...

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Autors principals: Leung, Kar-Wah, Ng, Hoi-Man, Tang, Maggie K. S., Wong, Chris C. K., Wong, Ricky N. S., Wong, Alice S. T.
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214261/
https://ncbi.nlm.nih.gov/pubmed/21964931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-011-9235-z
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