Impaired Rho GTPase activation abrogates cell polarization and migration in macrophages with defective lipolysis

Infiltration of monocytes and macrophages into the site of inflammation is critical in the progression of inflammatory diseases such as atherosclerosis. Cell migration is dependent on the continuous organization of the actin cytoskeleton, which is regulated by members of the small Rho GTPase family...

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Autors principals: Aflaki, Elma, Balenga, Nariman A. B., Luschnig-Schratl, Petra, Wolinski, Heimo, Povoden, Silvia, Chandak, Prakash G., Bogner-Strauss, Juliane G., Eder, Sandra, Konya, Viktoria, Kohlwein, Sepp-Dieter, Heinemann, Akos, Kratky, Dagmar
Format: Artigo
Idioma:Inglês
Publicat: SP Birkhäuser Verlag Basel 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214256/
https://ncbi.nlm.nih.gov/pubmed/21533980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-011-0688-4
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