Impaired Rho GTPase activation abrogates cell polarization and migration in macrophages with defective lipolysis

Infiltration of monocytes and macrophages into the site of inflammation is critical in the progression of inflammatory diseases such as atherosclerosis. Cell migration is dependent on the continuous organization of the actin cytoskeleton, which is regulated by members of the small Rho GTPase family...

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Detalhes bibliográficos
Main Authors: Aflaki, Elma, Balenga, Nariman A. B., Luschnig-Schratl, Petra, Wolinski, Heimo, Povoden, Silvia, Chandak, Prakash G., Bogner-Strauss, Juliane G., Eder, Sandra, Konya, Viktoria, Kohlwein, Sepp-Dieter, Heinemann, Akos, Kratky, Dagmar
Formato: Artigo
Idioma:Inglês
Publicado em: SP Birkhäuser Verlag Basel 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214256/
https://ncbi.nlm.nih.gov/pubmed/21533980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-011-0688-4
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