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Hepatitis B virus core promoter mutations G1613A and C1653T are significantly associated with hepatocellular carcinoma in genotype C HBV-infected patients

BACKGROUND: Hepatitis B virus (HBV) is a major cause of hepatocarcinogenesis. To identify mutations relevant to hepatocellular carcinoma (HCC) development, we compared the full genome sequences of HBV from the sera of patients with and without HCC. METHODS: We compared the full genome sequences of H...

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Detalhes bibliográficos
Main Authors: Tatsukawa, Masashi, Takaki, Akinobu, Shiraha, Hidenori, Koike, Kazuko, Iwasaki, Yoshiaki, Kobashi, Haruhiko, Fujioka, Shin-Ichi, Sakaguchi, Kohsaku, Yamamoto, Kazuhide
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214198/
https://ncbi.nlm.nih.gov/pubmed/22014121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-458
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