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Virus-Host Cell Interactions during Hepatitis C Virus RNA Replication: Impact of Polyprotein Expression on the Cellular Transcriptome and Cell Cycle Association with Viral RNA Synthesis

Considerable controversy surrounds the impact of hepatitis C virus (HCV) protein expression on viability of host cells and regulation of the cell cycle. Both promotion of cellular proliferation and apoptosis have been observed in different experimental systems. To determine whether expression of the...

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Autori principali: Scholle, Frank, Li, Kui, Bodola, Francis, Ikeda, Masanori, Luxon, Bruce A., Lemon, Stanley M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC321413/
https://ncbi.nlm.nih.gov/pubmed/14722306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.3.1513-1524.2004
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