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Modulation of inhibitory strength and kinetics facilitates regulation of persistent inward currents and motoneuron excitability following spinal cord injury

Spasticity is commonly observed after chronic spinal cord injury (SCI) and many other central nervous system disorders (e.g., multiple sclerosis, stroke). SCI-induced spasticity has been associated with motoneuron hyperexcitability partly due to enhanced activation of intrinsic persistent inward cur...

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Detalhes bibliográficos
Main Authors: Venugopal, Sharmila, Hamm, Thomas M., Crook, Sharon M., Jung, Ranu
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214109/
https://ncbi.nlm.nih.gov/pubmed/21775715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00359.2011
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