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Fucoidan Extract Induces Apoptosis in MCF-7 Cells via a Mechanism Involving the ROS-Dependent JNK Activation and Mitochondria-Mediated Pathways

BACKGROUND: Fucoidan extract (FE), an enzymatically digested compound with a low molecular weight, is extracted from brown seaweed. As a natural compound with various actions, FE is attractive, especially in Asian countries, for improving the therapeutic efficacy and safety of cancer treatment. The...

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Detalhes bibliográficos
Main Authors: Zhang, Zhongyuan, Teruya, Kiichiro, Eto, Hiroshi, Shirahata, Sanetaka
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214060/
https://ncbi.nlm.nih.gov/pubmed/22096572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027441
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