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Regulation of monocyte subset proinflammatory responses within the lung microvasculature by the p38 MAPK/MK2 pathway

Margination and activation of monocytes within the pulmonary microcirculation contribute substantially to the development of acute lung injury in mice. The enhanced LPS-induced TNF expression exhibited by Gr-1(high) compared with Gr-1(low) monocytes within the lung microvasculature suggests differen...

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Autors principals: O'Dea, Kieran P., Dokpesi, Justina O., Tatham, Kate C., Wilson, Michael R., Takata, Masao
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213987/
https://ncbi.nlm.nih.gov/pubmed/21873449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00092.2011
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