A cis-Acting Replication Element in the Sequence Encoding the NS5B RNA-Dependent RNA Polymerase Is Required for Hepatitis C Virus RNA Replication

RNA structures play key roles in the replication of RNA viruses. Sequence alignment software, thermodynamic RNA folding programs, and classical comparative phylogenetic analysis were used to build models of six RNA elements in the coding region of the hepatitis C virus (HCV) RNA-dependent RNA polyme...

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Autors principals: You, Shihyun, Stump, Decherd D., Branch, Andrea D., Rice, Charles M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Replication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC321395/
https://ncbi.nlm.nih.gov/pubmed/14722290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.3.1352-1366.2004
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