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Light-initiated hydroxylation of lauric acid using hybrid P450 BM3 enzymes()

We have developed hybrid P450 BM3 enzymes consisting of a Ru(II)-diimine photosensitizer covalently attached to non-native single cysteine residues of P450 BM3 heme domain mutants. These enzymes are capable, upon light activation, of selectively hydroxylating lauric acid with 40 times higher total t...

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Autores principales: Tran, Ngoc-Han, Huynh, Ngoc, Bui, Thuba, Nguyen, Yen, Huynh, Phuong, Cooper, Mary E., Cheruzel, Lionel E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213755/
https://ncbi.nlm.nih.gov/pubmed/21975564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1cc15124j
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