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The C313Y Piedmontese mutation decreases myostatin covalent dimerisation and stability
BACKGROUND: Myostatin is a key negative regulator of muscle growth and development, whose activity has important implications for the treatment of muscle wastage disorders. Piedmontese cattle display a double-muscled phenotype associated with the expression of C313Y mutant myostatin. In vivo, C313Y...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3213697/ https://ncbi.nlm.nih.gov/pubmed/22023879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-4-442 |
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