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Effects of Blocking Individual Maturation Cleavages in Murine Leukemia Virus Gag

A single protein, termed Gag, is responsible for retrovirus particle assembly. After the assembled virion is released from the cell, Gag is cleaved at several sites by the viral protease (PR). The cleavages catalyzed by PR bring about a wide variety of physical changes in the particle, collectively...

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Udgivet i:J Virol
Principais autores: Oshima, Masamichi, Muriaux, Delphine, Mirro, Jane, Nagashima, Kunio, Dryden, Kelly, Yeager, Mark, Rein, Alan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
Fag:
Structure and Assembly
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321369/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14722296/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.3.1411-1420.2004
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