Potential penetration of topical ranibizumab (Lucentis) in the rabbit eye

PURPOSE: To assess ranibizumab (Lucentis) penetration into the retina after topical administration in a rabbit model. METHODS: Ranibizumab was topically applied to the right eye of rabbits according to three regimens: every 2 h (q2hr), four times daily (qid), and twice daily (bid). Intraocular penet...

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Main Authors: Chen, J J, Ebmeier, S E, Sutherland, W M, Ghazi, N G
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Laboratory Study
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213670/
https://ncbi.nlm.nih.gov/pubmed/21921952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/eye.2011.225
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