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Both the PPPY and PTAP Motifs Are Involved in Human T-Cell Leukemia Virus Type 1 Particle Release

In retroviruses, the late (L) domain has been defined as a conserved motif in the Gag polyprotein precursor that, when mutated, leads to the emergence of virus particles that fail to pinch off from the plasma membrane. These domains have been observed to contain the PPXY, PTAP, or YXXL motifs. The d...

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Bibliographic Details
Main Authors: Wang, Huating, Machesky, Nicholas J., Mansky, Louis M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC321366/
https://ncbi.nlm.nih.gov/pubmed/14722305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.3.1503-1512.2004
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