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Endothelin B receptor contribution to peripheral microvascular function in women with polycystic ovary syndrome

ABSTRACT: Endothelin-1 is elevated in women with polycystic ovary syndrome (PCOS), and may play a role in the endothelial dysfunction associated with PCOS. Endothelin-1 binds two receptor subtypes, endothelin A (ET-A) and endothelin B (ET-B). We hypothesized that ET-A mediates vasoconstriction in th...

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Autors principals: Wenner, Megan M, Taylor, Hugh S, Stachenfeld, Nina S
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213415/
https://ncbi.nlm.nih.gov/pubmed/21825025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.216218
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