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Mutation Altering the miR-184 Seed Region Causes Familial Keratoconus with Cataract
MicroRNAs (miRNAs) bind to complementary sequences within the 3′ untranslated region (UTR) of mRNAs from hundreds of target genes, leading either to mRNA degradation or suppression of translation. We found that a mutation in the seed region of miR-184 (MIR184) is responsible for familial severe kera...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3213395/ https://ncbi.nlm.nih.gov/pubmed/21996275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2011.09.014 |
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