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Functional interactions between Choline kinase α, epidermal growth factor receptor (EGFR), and c-Src in breast cancer cell proliferations

EGFR family members and c-Src are co-overexpressed in many cancers. The synergistic effect of EGFR and c-Src has been shown in the tumorigenesis of breast and other cancers. Reported mechanisms of synergy include transcriptional regulation by STAT5b and the regulation of cellular ATP production by m...

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Bibliographic Details
Main Authors: Miyake, Tsuyoshi, Parsons, Sarah J.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213328/
https://ncbi.nlm.nih.gov/pubmed/21822308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.332
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