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Pharmacogenetic analysis of the effects of polymorphisms in APOE, IDE and IL1B on a ketone body based therapeutic on cognition in mild to moderate Alzheimer's disease; a randomized, double-blind, placebo-controlled study

BACKGROUND: To examine the effect of genetic variation in APOE, IDE and IL1B on the response to induced ketosis in the Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-Cog) in subjects with mild to moderate Alzheimer's disease (AD). METHODS: Genotype effects on ADAS-Cog scores...

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Detalhes bibliográficos
Main Authors: Henderson, Samuel T, Poirier, Judes
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213220/
https://ncbi.nlm.nih.gov/pubmed/21992747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-12-137
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