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Nicotinic Cholinergic Synaptic Mechanisms in the Ventral Tegmental Area Contribute to Nicotine Addiction

Tobacco use is a major health problem that is estimated to cause 4 million deaths a year worldwide. Nicotine is the main addictive component of tobacco. It acts as an agonist to activate and desensitize nicotinic acetylcholine receptors (nAChRs). A component of nicotine's addictive power is att...

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Main Authors: Pidoplichko, Volodymyr I., Noguchi, Jun, Areola, Oluwasanmi O., Liang, Yong, Peterson, Jayms, Zhang, Tianxiang, Dani, John A.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC321315/
https://ncbi.nlm.nih.gov/pubmed/14747518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.70004
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