The evolution of pyrimethamine resistant dhfr in Plasmodium falciparum of south-eastern Tanzania: comparing selection under SP alone vs SP+artesunate combination

BACKGROUND: Sulphadoxine-pyrimethamine (SP) resistance is now widespread throughout east and southern Africa and artemisinin compounds in combination with synthetic drugs (ACT) are recommended as replacement treatments by the World Health Organization (WHO). As well as high cure rates, ACT has been...

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Bibliografske podrobnosti
Main Authors: Malisa, Allen L, Pearce, Richard J, Mutayoba, Ben M, Abdullah, Salim, Mshinda, Hassan, Kachur, Patrick S, Bloland, Peter, Roper, Cally
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213132/
https://ncbi.nlm.nih.gov/pubmed/22029848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-10-317
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