Evolution of Multidrug Resistance during Staphylococcus aureus Infection Involves Mutation of the Essential Two Component Regulator WalKR

Antimicrobial resistance in Staphylococcus aureus is a major public health threat, compounded by emergence of strains with resistance to vancomycin and daptomycin, both last line antimicrobials. Here we have performed high throughput DNA sequencing and comparative genomics for five clinical pairs of...

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Hlavní autoři: Howden, Benjamin P., McEvoy, Christopher R. E., Allen, David L., Chua, Kyra, Gao, Wei, Harrison, Paul F., Bell, Jan, Coombs, Geoffrey, Bennett-Wood, Vicki, Porter, Jessica L., Robins-Browne, Roy, Davies, John K., Seemann, Torsten, Stinear, Timothy P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213104/
https://ncbi.nlm.nih.gov/pubmed/22102812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002359
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