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Association between copy number variation of complement component C4 and Graves' disease

BACKGROUND: Gene copy number of complement component C4, which varies among individuals, may determine the intrinsic strength of the classical complement pathway. Presuming a major role of complement as an effecter in peptide-mediated inflammation and phagocytosis, we hypothesized that C4 genetic di...

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Detalhes bibliográficos
Main Authors: Liu, Yu-Huei, Wan, Lei, Chang, Chwen-Tzuei, Liao, Wen-Ling, Chen, Wen-Chi, Tsai, Yuhsin, Tsai, Chang-Hai, Tsai, Fuu-Jen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212822/
https://ncbi.nlm.nih.gov/pubmed/21943165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-18-71
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