Ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) is a potential tumour suppressor in prostate cancer and is frequently silenced by promoter methylation

BACKGROUND: We have previously reported significant downregulation of ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) in prostate cancer (PCa) compared to the surrounding benign tissue. UCHL1 plays an important role in ubiquitin system and different cellular processes such as cell proliferation and...

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Detalhes bibliográficos
Main Authors: Ummanni, Ramesh, Jost, Edgar, Braig, Melanie, Lohmann, Frithjof, Mundt, Frederike, Barett, Christine, Schlomm, Thorsten, Sauter, Guido, Senff, Tina, Bokemeyer, Carsten, Sültmann, Holger, Meyer-Schwesinger, Catherine, Brümmendorf, Tim H, Balabanov, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212821/
https://ncbi.nlm.nih.gov/pubmed/21999842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-129
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