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Organocatalyzed enantioselective synthesis of 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylates

The organocatalyzed enantioselective synthesis of biologically active 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate derivatives was achieved using bifunctional cinchona alkaloids as the catalysts. Using quinine thiourea as the catalyst, the tandem Michael addition-cyclization reaction b...

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Autori principali: Ramireddy, Naresh, Abbaraju, Santhi, Zhao, Cong-Gui
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212733/
https://ncbi.nlm.nih.gov/pubmed/22081731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2011.10.040
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