Pretreatment Strategy with Adenosine A(2A) Receptor Agonist Attenuates Reperfusion Injury in a Preclinical Porcine Lung Transplantation Model

OBJECTIVES: Adenosine A(2A) receptor (A(2A)R) activation following lung transplantation attenuates ischemia-reperfusion (IR) injury by reducing inflammation. However, the effect of A(2A)R activation in donor lungs prior to transplant remains ill-defined. This study compares the efficacy of three dif...

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Autori principali: LaPar, Damien J., Laubach, Victor E., Emaminia, Abbas, Crosby, Ivan K., Hajzus, Vanessa A., Sharma, Ashish K., Sumner, Heather M., Webb, David V., Lau, Christine L., Kron, Irving L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212732/
https://ncbi.nlm.nih.gov/pubmed/21762933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2011.06.015
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