Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy

Radiotherapy is one of the most successful cancer therapies. Here the effect of irradiation on antigen presentation by MHC class I molecules was studied. Cell surface expression of MHC class I molecules was increased for many days in a radiation dose-dependent manner as a consequence of three respon...

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主要な著者: Reits, Eric A., Hodge, James W., Herberts, Carla A., Groothuis, Tom A., Chakraborty, Mala, K.Wansley, Elizabeth, Camphausen, Kevin, Luiten, Rosalie M., de Ru, Arnold H., Neijssen, Joost, Griekspoor, Alexander, Mesman, Elly, Verreck, Frank A., Spits, Hergen, Schlom, Jeffrey, van Veelen, Peter, Neefjes, Jacques J.
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2006
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Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212727/
https://ncbi.nlm.nih.gov/pubmed/16636135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20052494
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