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Mutagen-Specific Mutation Signature Determines Global microRNA Binding
Micro-RNAs (miRNAs) are small non-coding RNAs that regulate gene products at the post-transcriptional level. It is thought that loss of cell regulation by miRNAs supports cancer development. Based on whole genome sequencing of a melanoma tumor, we predict, using three different computational algorit...
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Auteurs principaux: | , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
Public Library of Science
2011
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3212558/ https://ncbi.nlm.nih.gov/pubmed/22096567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027400 |
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