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Differential Immediate and Sustained Memory Enhancing Effects of Alpha7 Nicotinic Receptor Agonists and Allosteric Modulators in Rats

The α7 nicotinic acetylcholine receptor (nAChR) is a potential target for the treatment of cognitive deficits in patients with schizophrenia, ADHD and Alzheimer's disease. Here we test the hypothesis that upregulation of α7 nAChR levels underlies the enhanced and sustained procognitive effect o...

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Bibliografiske detaljer
Main Authors: Thomsen, Morten S., El-Sayed, Mona, Mikkelsen, Jens D.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212529/
https://ncbi.nlm.nih.gov/pubmed/22096516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027014
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