Toll-Like Receptors 2 and 4 Regulate the Frequency of IFNγ-Producing CD4(+) T-Cells during Pulmonary Infection with Chlamydia pneumoniae

TLR2 and TLR4 are crucial for recognition of Chlamydia pneumoniae in vivo, since infected TLR2/4 double-deficient mice are unable to control the infection as evidenced by severe loss of body weight and progressive lethal pneumonia. Unexpectedly, these mice display higher pulmonary levels of the prot...

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Detalhes bibliográficos
Main Authors: Wantia, Nina, Rodriguez, Nuria, Cirl, Christine, Ertl, Tanja, Dürr, Susanne, Layland, Laura E., Wagner, Hermann, Miethke, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212512/
https://ncbi.nlm.nih.gov/pubmed/22096480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026101
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