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Crystallization and preliminary X-ray crystallographic studies of the PYD domain of human NALP3

The NALP3 inflammasome is a macromolecular complex that is responsible for the innate immune response against infection by bacterial and viral pathogens. The NALP3 inflammasome is composed of three protein components: NALP3, ASC and caspase 1. Interaction between NALP3 and ASC via PYD domains is cri...

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Detalhes bibliográficos
Main Authors: Bae, Ju Young, Park, Hyun Ho
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212466/
https://ncbi.nlm.nih.gov/pubmed/22102247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111035937
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