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Crystallization and preliminary X-ray crystallographic studies of the PYD domain of human NALP3
The NALP3 inflammasome is a macromolecular complex that is responsible for the innate immune response against infection by bacterial and viral pathogens. The NALP3 inflammasome is composed of three protein components: NALP3, ASC and caspase 1. Interaction between NALP3 and ASC via PYD domains is cri...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
International Union of Crystallography
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3212466/ https://ncbi.nlm.nih.gov/pubmed/22102247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111035937 |
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