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Cloning, overexpression, purification, crystallization and preliminary X-ray analysis of 3-­ketosteroid Δ(4)-(5α)-dehydrogenase from Rhodococcus jostii RHA1

3-Ketosteroid dehydrogenases are flavoproteins which play key roles in steroid ring degradation. The enzymes are abundantly present in actinobacteria, including the catabolic powerhouse Rhodococcus jostii and the pathogenic species R. equi and Mycobacterium tuberculosis. The gene for 3-ketosteroid Δ...

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Detalhes bibliográficos
Main Authors: van Oosterwijk, Niels, Knol, Jan, Dijkhuizen, Lubbert, van der Geize, Robert, Dijkstra, Bauke W.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212380/
https://ncbi.nlm.nih.gov/pubmed/22102045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111028727
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