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Adaptive increase of O6-methylguanine-acceptor protein in HeLa cells following N-methyl-N'-nitro-N-nitrosoguanidine treatment.

We have assayed in extracts of HeLa cells the amount of acceptor protein that removes O6-methylguanine adducts from alkylated DNA. Cells were treated with single or multiple nontoxic doses of N-methyl-N'-nitrosoguanidine (MNNG) and the extracts were analyzed up to 32 h after the last exposure....

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Dettagli Bibliografici
Autori principali: Waldstein, E A, Cao, E H, Setlow, R B
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1982
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC321114/
https://ncbi.nlm.nih.gov/pubmed/7133992
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