Adaptive increase of O6-methylguanine-acceptor protein in HeLa cells following N-methyl-N'-nitro-N-nitrosoguanidine treatment.
We have assayed in extracts of HeLa cells the amount of acceptor protein that removes O6-methylguanine adducts from alkylated DNA. Cells were treated with single or multiple nontoxic doses of N-methyl-N'-nitrosoguanidine (MNNG) and the extracts were analyzed up to 32 h after the last exposure. The a...
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| Publicado en: | Nucleic Acids Res |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
1982
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| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321114/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7133992/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/10.15.4595 |
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