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Experimental Evolution Reveals Antagonistic Pleiotropy in Reproductive Timing but Not Life Span in Caenorhabditis elegans
Many mutations that dramatically extend life span in model organisms come with substantial fitness costs. Although these genetic manipulations provide valuable insight into molecular modulators of life span, it is currently unclear whether life-span extension is unavoidably linked to fitness costs....
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3210959/ https://ncbi.nlm.nih.gov/pubmed/21975091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glr143 |
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