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Experimental Evolution Reveals Antagonistic Pleiotropy in Reproductive Timing but Not Life Span in Caenorhabditis elegans

Many mutations that dramatically extend life span in model organisms come with substantial fitness costs. Although these genetic manipulations provide valuable insight into molecular modulators of life span, it is currently unclear whether life-span extension is unavoidably linked to fitness costs....

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Bibliographic Details
Main Authors: Anderson, Jennifer L., Reynolds, Rose M., Morran, Levi T., Tolman-Thompson, Julie, Phillips, Patrick C.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210959/
https://ncbi.nlm.nih.gov/pubmed/21975091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glr143
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