Lack of Interleukin-1α or Interleukin-1β Inhibits Transformation of Steatosis to Steatohepatitis and Liver Fibrosis in Hypercholesterolemic Mice

BACKGROUND: The identification of the cellular and molecular pathways that mediate the development of non-alcoholic steatohepatitis is of crucial importance. Cytokines produced by liver-resident and infiltrating inflammatory cells, play a pivotal role in liver inflammation. The role of the proinflam...

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Detalhes bibliográficos
Main Authors: Kamari, Yehuda, Shaish, Aviv, Vax, Einav, Shemesh, Shay, Kandel-Kfir, Michal, Arbel, Yaron, Olteanu, Sarita, Barshack, Iris, Dotan, Shahar, Voronov, Elana, Dinarello, Charles A., Apte, Ron N., Harats, Dror
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210940/
https://ncbi.nlm.nih.gov/pubmed/21354232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2011.01.048
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