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Farnesol Decreases Biofilms of Staphylococcus epidermidis and Exhibits Synergy with Nafcillin and Vancomycin

Biofilm infections are frequently caused by S. epidermidis, are resistant to antimicrobial agents and adversely affect patient outcomes. We evaluated farnesol, the Candida quorum sensing molecule, on S. epidermidis biofilms, in vitro and in vivo. We evaluated ED(50), ED(75) and ED(90) –(drug concent...

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Bibliografiske detaljer
Main Authors: Pammi, Mohan, Liang, Rong, Hicks, John M., Barrish, Jim, Versalovic, James
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210893/
https://ncbi.nlm.nih.gov/pubmed/21857375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e318232a984
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