Progesterone receptor polymorphisms and clinical response to 17-alpha-hydroxyprogesterone caproate

OBJECTIVE: 17 alpha-hydroxyprogesterone caproate (17-OHPC) reduces recurrent preterm birth (PTB). We hypothesized that single nucleotide polymorphisms (SNPs) in the human progesterone receptor (PGR) will affect response to 17-OHPC in the prevention of recurrent PTB. STUDY DESIGN: Secondary analysis...

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Main Authors: Manuck, Tracy A., Lai, Yinglei, Meis, Paul J., Dombrowski, Mitchell P., Sibai, Baha, Spong, Catherine Y., Rouse, Dwight J., Durnwald, Celeste P., Caritis, Steve N., Wapner, Ronald J., Mercer, Brian M., Ramin, Susan M.
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210889/
https://ncbi.nlm.nih.gov/pubmed/21600550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2011.03.048
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