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Computational Modeling of Interactions between Multiple Myeloma and the Bone Microenvironment

Multiple Myeloma (MM) is a B-cell malignancy that is characterized by osteolytic bone lesions. It has been postulated that positive feedback loops in the interactions between MM cells and the bone microenvironment form reinforcing ‘vicious cycles’, resulting in more bone resorption and MM cell popul...

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Autors principals: Wang, Yan, Pivonka, Peter, Buenzli, Pascal R., Smith, David W., Dunstan, Colin R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210790/
https://ncbi.nlm.nih.gov/pubmed/22110661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027494
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