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High Glucose Promotes Pancreatic Cancer Cell Proliferation via the Induction of EGF Expression and Transactivation of EGFR

Multiple lines of evidence suggest that a large portion of pancreatic cancer patients suffer from either hyperglycemia or diabetes, both of which are characterized by high blood glucose level. However, the underlying biological mechanism of this phenomenon is largely unknown. In the present study, w...

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Bibliographic Details
Main Authors: Han, Liang, Ma, Qingyong, Li, Junhui, Liu, Han, Li, Wei, Ma, Guodong, Xu, Qinhong, Zhou, Shuang, Wu, Erxi
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210779/
https://ncbi.nlm.nih.gov/pubmed/22087246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027074
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