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Chemical and genetic engineering of selective ligand-ion channel interactions
Ionic flux in defined cell populations mediates essential physiological and behavioral functions. Cell type-specific activators of diverse ionic conductances are needed for probing these relationships. We combined chemistry and protein engineering to enable systematic creation of a toolbox of ligand...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3210548/ https://ncbi.nlm.nih.gov/pubmed/21885782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1206606 |
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