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A Food Restriction Protocol that Increases Drug Reward Decreases TrkB in the Ventral Tegmental Area, with No Effect on BDNF or TrkB Protein Levels in Dopaminergic Forebrain Regions

Food restriction (FR) decreases BDNF expression in hypothalamic and hindbrain regions that regulate feeding and metabolic efficiency, while increasing expression in hippocampal and neocortical regions. Drugs of abuse alter BDNF expression within the mesocorticolimbic dopamine (DA) pathway, and modif...

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Autors principals: Pan, Yan, Chau, Lily, Liu, Shan, Avshalumov, Marat V., Rice, Margaret E., Carr, Kenneth D.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210415/
https://ncbi.nlm.nih.gov/pubmed/21945647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2011.08.065
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