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Increased endoplasmic reticulum stress in decidual tissue from pregnancies complicated by fetal growth restriction with and without pre-eclampsia

OBJECTIVES: Endoplasmic reticulum (ER) stress has been implicated in both pre-eclampsia (PE) and fetal growth restriction (FGR), and is characterised by activation of three signalling branches: 1) PERK-pEIF2α, 2) ATF6 and 3) splicing of XBP1(U) into XBP1(S). To evaluate the contribution of ER stress...

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Detalhes bibliográficos
Main Authors: Lian, I.A., Løset, M., Mundal, S.B., Fenstad, M.H., Johnson, M.P., Eide, I.P., Bjørge, L., Freed, K.A., Moses, E.K., Austgulen, R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210381/
https://ncbi.nlm.nih.gov/pubmed/21907405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2011.08.005
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