Postnatal Serotonin Type 2 Receptor Blockade Prevents the Emergence of Anxiety Behavior, Dysregulated Stress-Induced Immediate Early Gene Responses, and Specific Transcriptional Changes that Arise Following Early Life Stress

BACKGROUND: Early life adverse experience contributes to an enhanced vulnerability for adult psychopathology. Recent evidence indicates that serotonin type 2 (5-HT(2)) receptor function, implicated in the pathophysiology of mood and anxiety disorders, is significantly enhanced in the maternal separa...

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Autors principals: Benekareddy, Madhurima, Vadodaria, Krishna C., Nair, Amrita R., Vaidya, Vidita A.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2011
Matèries:
Archival Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210326/
https://ncbi.nlm.nih.gov/pubmed/21959103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2011.08.005
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