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Antimelanogenic effect of c-phycocyanin through modulation of tyrosinase expression by upregulation of ERK and downregulation of p38 MAPK signaling pathways

BACKGROUND: Pigmentation is one of the essential defense mechanisms against oxidative stress or UV irradiation; however, abnormal hyperpigmentation in human skin may pose a serious aesthetic problem. C-phycocyanin (Cpc) is a phycobiliprotein from spirulina and functions as an antioxidant and a light...

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Detalhes bibliográficos
Main Authors: Wu, Li-Chen, Lin, Yu-Yun, Yang, Szu-Yen, Weng, Yu-Ting, Tsai, Yi-Ting
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210093/
https://ncbi.nlm.nih.gov/pubmed/21988805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-18-74
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